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Borage is a European herb that now also grows widely in North America. It has been used to treat depression and fever but its effectiveness is not proven. The oil made from its seeds is a source of gamma linolenic acid (GLA), an omega-6 fatty acid. Borage oil is sometimes recommended for rheumatoid arthritis.
GLA has been reported to lower the seizure threshold (which would make seizures more likely), but some studies with animals have found an antiseizure effect from fatty acids.
Read more about borage in the "About Herbs" section of the Memorial Sloan-Kettering Cancer Center website. (If you have not visited the site before, the information on borage will be preceded by a Disclaimer.)
Much of the information in this article is based on Spinella M: Herbal medicines and epilepsy: The potential for benefit and adverse effects. Epilepsy Behav 2001; 2(6):524-532. (PMID 12609386)
Topic Editor: Steven C. Schachter, M.D.
Last Reviewed:12/15/06
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